Metformin also raises your risk, so taking it if you have liver problems is dangerous. Alcohol use Drinking alcohol while taking metformin raises your risk of hypoglycemia. In patients with PCOS, metformin, which tends to reduce insulin resistance, is sometimes prescribed in an attempt to restore ovulation and to improve fertility. If pregnancy is confirmed, metformin is usually continued for at least the first trimester. Always talk with your doctor about your treatment options. Polycystic ovary syndrome is the most common endocrinological disorder affecting 4–12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Health Tips If You Are Taking Metformin For PCOS Do not take metformin for PCOS if you have a liver of kidney problem. Drink enough water to keep yourself hydrated while you are on Metformin. Taking metformin alone for PCOS does not cause hypoglycemia or low blood sugar. However, metformin, when accompanied with an unhealthy lifestyle, can lead to hypoglycemia. If you eat a poor diet, consume excessive alcohol, or perform strenuous exercises, you are at a risk of becoming hypoglycemic. Metformin can impact weight loss, infertility, acne, and other PCOS-related symptoms, however, the results are variable. There are also many side effects of Metformin that can have a negative impact your health. Most people think that aside from possible gastrointestinal upset, there are no side effects from taking metformin, and thus you can take it for a very long time. This is not true! The sneakiest side effect of all is a vitamin B12 insufficiency. Use of metformin throughout pregnancy in women with polycystic ovary syndrome (PCOS) has shown to reduce the rates of early pregnancy loss, preterm labor, and prevention of fetal growth restriction. If you’re taking the prescription drug metformin, you might have concerns about how the drug will affect your pregnancy. Let’s explore the benefits and any risks of using metformin while pregnant. If you have Polycystic Ovary Syndrome and have been prescribed metformin, chances are you have a lot of questions and concerns about taking this medication.